人结直肠癌细胞SW837

细胞名称

人结直肠癌细胞SW837

货物编码

BFN681361

产品规格

T25培养瓶x1

1.5ml冻存管x2

细胞数量

1x10^6

1x10^6

保存温度

37℃

-198℃

运输方式

常温保温运输

干冰运输

安全等级

1

用途限制

仅供科研   2类

培养体系

DMEM高糖（HYCLONE SH30022.01)+10%FBS+1%三抗

培养温度

37℃

二氧化碳浓度

5%

简介

人结直肠癌细胞SW837取自53岁男性供体，贴壁培养。

注释

Part of: AstraZeneca Colorectal cell line (AZCL) panel.

Part of: Cancer Cell Line Encyclopedia (CCLE) project.

Part of: COSMIC cell lines project.

Part of: FGFR genetic alteration cell panel (ATCC TCP-1034).

Part of: MD Anderson Cell Lines Project.

Part of: NCI RAS program mutant KRAS cell line panel.

Part of: TCGA-110-CL cell line panel.

From: Scott and White Clinic; Temple; USA.

Doubling time: 169 hours, at 5th passage (PubMed=1000501).

Microsatellite instability: Stable (MSS) (PubMed=25926053; PubMed=28683746; Sanger).

Omics: CNV analysis.

Omics: Deep exome analysis.

Omics: Deep proteome analysis.

Omics: Deep quantitative phosphoproteome analysis.

Omics: Deep quantitative proteome analysis.

Omics: Deep RNAseq analysis.

Omics: DNA methylation analysis.

Omics: miRNA expression profiling.

Omics: N-glycan profiling.

Omics: O-glycan profiling.

Omics: Protein expression by reverse-phase protein arrays.

Omics: SNP array analysis.

Omics: Transcriptome analysis.

Derived from sampling site: Rectum.

基因突变

APC p.Arg1450Ter (c.4348C>T) (ClinVar=VCV000194585) (PubMed=24755471).

FBXW7 p.Leu403fs*34 (c.1208_1209insT) (PubMed=24755471).

Heterozygous for KRAS p.Gly12Cys (c.34G>T) (ClinVar=VCV000012578) (PubMed=12068308; PubMed=20570890; PubMed=24755471; PubMed=28683746).

Hemizygous for TP53 p.Arg248Trp (c.742C>T) (ClinVar=VCV000012347) (PubMed=7651727; PubMed=9715273; PubMed=16418264; PubMed=24755471; PubMed=28683746).

HLA信息

/

STR信息

Amelogenin X

CSF1PO 10

D3S1358 18

D5S818 12

D7S820 9,12

D8S1179 8,14

D13S317 13

D16S539 12

D18S51 17

D21S11 28,31.2

FGA 25

Penta D 9,11

Penta E 11,12

TH01 9.3

TPOX 8,9

vWA 15,16

参考文献

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 Differential effector engagement by oncogenic KRAS.

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 Quantitative proteomics of the Cancer Cell Line Encyclopedia.

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